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Updated clinical practice recommendations regarding the periprocedural use of GLP-1RAs and GLP-1/GIPRAs (April 2025)


Based on new evidence from clinical studies and to make recommendations clearer, clinical practice recommendations for patients taking GLP-1 RA and dual GLP-1/GIP RAs prior to anaesthesia or sedation have been updated.

Representatives from the Australian Diabetes Society, Australian and New Zealand College of Anaesthetists, Gastroenterological Society of Australia, National Association of Clinical Obesity Services, and Australian & New Zealand Metabolic and Obesity Surgery Society have developed the revised recommendations, which now include a decision-aid flowchart linked to explanatory statements.

They now also include a clear statement regarding the recommendation not to withhold these drugs prior to a procedure.

The revised document is available here. Please send any feedback or queries to admin@diabetessociety.com.au